MUC1 (Mucin 1)
MUC1 (Mucin 1)
- Used for: Breast cancer, ovarian cancer, pancreatic cancer.
- Why it’s good: Overexpression of MUC1 is seen in many cancers, making it a broad biomarker.
- Limitation: It can be elevated in non-cancerous conditions as well.
TP53 (Tumor Protein p53)
Alpha-fetoprotein (AFP) is a protein normally produced by the fetal liver and yolk sac during development. In adults, AFP levels are usually very low, so an elevated AFP can be…
The Thomsen–Friedenreich (TF) antigen, also known as CD176, is a disaccharide structure comprising galactose and N-acetylgalactosamine (Galβ1-3GalNAcα1-Ser/Thr). It serves as the core 1 structure in O-linked glycosylation of proteins. In…
HER2/neu (Human Epidermal Growth Factor Receptor 2)
When it’s exposed, it can be detected by specific antibodies (like peanut agglutinin), and its presence is linked to disease processes. The Thomsen–Friedenreich antigen (T antigen) — sometimes called the…
EGFR (Epidermal Growth Factor Receptor)